RNF2 E3 or Not to E3: Dual Roles of RNF2 Overexpression in Melanoma.
نویسندگان
چکیده
RNF2/RING1B is amplified and overexpressed in numerous tumors and contributes to tumorigenicity; however, the biologic importance is poorly understood. Surprisingly, the role of RNF2 in tumorigenesis and invasion can be separated into catalytically independent and catalytically dependent processes.
منابع مشابه
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عنوان ژورنال:
- Cancer discovery
دوره 5 12 شماره
صفحات -
تاریخ انتشار 2015